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Research guide

Time to exhaustion research

A lab outcome that can still guide training: it often tracks fatigue resistance.

Updated Oct 17, 2026

What to do first

  • • Build durability: long sessions + steady weekly volume.
  • • Avoid stacking intensity when sleep is low.
  • • Track drift: pace vs heart rate vs RPE over time.

Related topic guides

Protocols and decisions connected to this outcome.

Study library (reference)

Source papers linked to this outcome.

study

Effects of Caffeine Intake on Endurance Running Performance and Time to Exhaustion: A Systematic Review and Meta-Analysis.

Human research · 2022 · Nutrients · PubMed 36615805

study

Carbohydrate ingestion during endurance exercise improves performance in adults.

Human research · 2011 · The Journal of nutrition · PubMed 21411610

study

Ergogenic effects of supplement combinations on endurance performance: a systematic review and meta-analysis of randomized controlled trials.

Human research · 2025 · Journal of the International Society of Sports Nutrition · PubMed 40619880

study

The ergogenic effects of acute carbohydrate feeding on endurance performance: a systematic review, meta-analysis and meta-regression.

Human research · 2024 · Critical reviews in food science and nutrition · PubMed 37449467

study

Post-exercise Ingestion of Carbohydrate, Protein and Water: A Systematic Review and Meta-analysis for Effects on Subsequent Athletic Performance.

Human research · 2018 · Sports medicine (Auckland, N.Z.) · PubMed 29098657

study

Effect of respiratory muscle training on exercise performance in healthy individuals: a systematic review and meta-analysis.

Human research · 2012 · Sports medicine (Auckland, N.Z.) · PubMed 22765281

study

Hydration Status After an Ironman Triathlon: A Meta-Analysis.

Population not classified in the source record · 2019 · Journal of human kinetics · PubMed 31915479

study

Effects of caffeine supplementation on muscle endurance, maximum strength, and perceived exertion in adults submitted to strength training: a systematic review and meta-analyses.

Human research · 2021 · Critical reviews in food science and nutrition · PubMed 32551869

study

Caffeine and Bicarbonate for Speed. A Meta-Analysis of Legal Supplements Potential for Improving Intense Endurance Exercise Performance.

Population not classified in the source record · 2017 · Frontiers in physiology · PubMed 28536531

study

Effects of protein in combination with carbohydrate supplements on acute or repeat endurance exercise performance: a systematic review.

Human research · 2014 · Sports medicine (Auckland, N.Z.) · PubMed 24343835

study

Effect of respiratory muscle training in asthma: A systematic review and meta-analysis.

Human research · 2023 · Annals of physical and rehabilitation medicine · PubMed 35843501

study

Nutritional Ergogenic Aids in Cycling: A Systematic Review.

Human research · 2024 · Nutrients · PubMed 38892701

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Sources