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Inducing Muscle Heat Shock Protein 70 Improves Insulin Sensitivity and Muscular Performance in Aged Mice.

Updated Oct 17, 2026

Animal researchThe journals of gerontology. Series A, Biological sciences and medical sciences2015Read the source on PubMed

What the study found

Heat treatment improved endurance in the aged mice, while heat and drug treatment improved insulin sensitivity. Several other muscle outcomes did not differ.

Participants and protocol

Aged mice on a Western diet received eight weeks of heat therapy, an experimental heat-shock-protein-inducing drug, or a control condition.

What this cannot establish

This is animal research. It does not establish a sauna prescription, drug recommendation or demonstrated longevity or endurance benefit in people.

Publication details
Record
PubMed 25123646
Publication types
research-article · Research Support, N.I.H., Extramural
Indexed subjects
Muscle, Skeletal · Mice, Inbred C57BL · Mice · Insulin Resistance · Diterpenes
Source record checked
2026-10-18

Publication type and subject indexing describe the record; they are not a quality grade or proof of a benefit. An abstract does not replace a review of the full methods and results.

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