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Study note

Global, regional, and national burden of tuberculosis and multidrug-resistant tuberculosis by HIV status, 1990-2023: a systematic analysis for the Global Burden of Disease Study 2023.

PMID 42385762 (2026): global, regional — Sleep quality, Recovery speed (study note for endurance athletes).

Updated Jul 22, 2026

Read the study note

Study note • PMID 42385762

Global, regional, and national burden of tuberculosis and multidrug-resistant tuberculosis by HIV status, 1990-2023: a systematic analysis for the Global Burden of Disease Study 2023.

The Lancet. Infectious diseases2026 • DOI 10.1016/S1473-3099(26)00295-1

How to use this page

This note summarizes one study record. Check the participants, methods, results, and limitations before applying it to training.

  • Design signal: controlled study.
  • Population relevance: mixed/unclear athlete specificity.
  • Consistency: single-study evidence.
  • Practical recommendation depends on tolerance, context, and whether it protects training consistency.

ELI5

In plain language

BACKGROUND: Tuberculosis (TB) is the leading global cause of death from a single infectious agent. (controlled study; participants).

The abstract suggests a trade-off or negative effect affecting Recovery speed. Treat this as a signal, not a guarantee; confirm methods and context in the full paper.

Takeaways

What the abstract suggests

  • Study question: BACKGROUND: Tuberculosis (TB) is the leading global cause of death from a single infectious agent.
  • The abstract suggests a trade-off or negative effect affecting Recovery speed.
  • Population: participants.
  • Protocol cues: abstract may omit dose/timing; use the full paper to replicate accurately.

Protocol

Protocol (as reported)

  • Intervention/exposure: global, regional.
  • Dose/time/duration: abstract doesn’t include enough detail; use the full paper’s methods section.
  • Outcomes: Sleep quality, Recovery speed.
  • Replication note: abstracts often omit adherence and timing; confirm details before changing training or supplementation.

Fit

Who it may help, and who should be cautious

Who it helps

  • Athletes similar to the study population (participants) working on sleep.
  • Athletes who can measure Sleep quality, Recovery speed with a repeatable workout or time-trial effort.

Who should be cautious

  • If you have symptoms or conditions that make the intervention risky, get professional guidance.
  • If you’re near race day and can’t safely test, defer the experiment.

Methods

What the study actually did

  • Design: controlled study.
  • Population: participants.
  • Outcomes measured: Sleep quality, Recovery speed.
  • Source: PubMed PMID 42385762 (2026) — The Lancet. Infectious diseases.

Results excerpt

What the abstract reports

Removing smoking, alcohol use, and high fasting plasma glucose would reduce global TB deaths to 768 000 (592 000-970 000) and DALYs to 34.9 million (27.8-43.8) in 2023; MDR-TB deaths would decrease to 77 200 (23 400-183 000) and DALYs to 3.12 million (1.03-7.29).

Note: excerpts are short; for full context, read the paper.

Limits

Limitations and bias

  • Abstract-only summaries can miss critical details (population, protocol, adherence, and context).
  • Single studies often don’t generalize to your event, history, and training load; treat results as a starting point.
  • If your context differs (elite vs recreational; cycling vs running), adjust expectations and be conservative.
  • This is performance information, not medical advice.

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