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Study note

Acute ingestion of snake fruit jelly improves glycemic response, enhances endurance performance and antioxidant defense, and reduces inflammatory markers in healthy adults.

PMID 41139389 (2025): glucose — Time to exhaustion, Time-trial performance, Fat oxidation (study note for endurance athletes).

Updated Jul 22, 2026

Read the study note

Study note • PMID 41139389

Acute ingestion of snake fruit jelly improves glycemic response, enhances endurance performance and antioxidant defense, and reduces inflammatory markers in healthy adults.

Journal of the International Society of Sports Nutrition2025 • DOI 10.1080/15502783.2025.2579029

How to use this page

This note summarizes one study record. Check the participants, methods, results, and limitations before applying it to training.

  • Design signal: randomized trial.
  • Population relevance: mixed/unclear athlete specificity.
  • Consistency: single-study evidence.
  • Practical recommendation depends on tolerance, context, and whether it protects training consistency.

ELI5

In plain language

BACKGROUND: Snake fruit is rich in vitamin C, carotene, phenolic compounds, flavonoids, and monoterpenoids - bioactive constituents known for their potent antioxidant properties. (randomized trial; n=25 participants).

The abstract doesn’t indicate a clear change in Time to exhaustion, Time-trial performance under the tested conditions. Treat this as a signal, not a guarantee; confirm methods and context in the full paper.

Takeaways

What the abstract suggests

  • Study question: BACKGROUND: Snake fruit is rich in vitamin C, carotene, phenolic compounds, flavonoids, and monoterpenoids - bioactive constituents known for their potent antioxidant properties.
  • The abstract doesn’t indicate a clear change in Time to exhaustion, Time-trial performance under the tested conditions.
  • Population: n=25 participants.
  • Protocol cues (title/abstract): 30 minutes • 2 hours • 60 minutes • 120 minutes.

Protocol

Protocol (as reported)

  • Intervention/exposure: glucose (vs comparison group).
  • Dose/time/duration cues in abstract/title: 30 minutes • 2 hours • 60 minutes • 120 minutes.
  • Outcomes: Time to exhaustion, Time-trial performance, Fat oxidation.
  • Replication note: abstracts often omit adherence and timing; confirm details before changing training or supplementation.

Fit

Who it may help, and who should be cautious

Who it helps

  • Athletes similar to the study population (n=25 participants) working on fueling.
  • Athletes who can measure Time to exhaustion, Time-trial performance, Fat oxidation with a repeatable workout or time-trial effort.

Who should be cautious

  • If you have symptoms or conditions that make the intervention risky, get professional guidance.
  • If you’re near race day and can’t safely test, defer the experiment.

Methods

What the study actually did

  • Design: randomized trial.
  • Population: n=25 participants.
  • Comparator: comparison group.
  • Outcomes measured: Time to exhaustion, Time-trial performance, Fat oxidation.
  • Protocol cues mentioned: 30 minutes • 2 hours • 60 minutes • 120 minutes.
  • Source: PubMed PMID 41139389 (2025) — Journal of the International Society of Sports Nutrition.

Results excerpt

What the abstract reports

In Experiment 1, BG concentrations at 30 and 60 minutes post-ingestion, as well as the incremental area under the BG curve at 30, 60, 90, and 120 minutes, were significantly lower following snake fruit jelly ingestion compared with control (all p < 0.05).

Note: excerpts are short; for full context, read the paper.

Limits

Limitations and bias

  • Abstract-only summaries can miss critical details (population, protocol, adherence, and context).
  • Single studies often don’t generalize to your event, history, and training load; treat results as a starting point.
  • If your context differs (elite vs recreational; cycling vs running), adjust expectations and be conservative.
  • This is performance information, not medical advice.

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