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Does High-Intensity Interval Training Increase Muscle Strength, Muscle Mass, and Muscle Endurance? A Systematic Review and Meta-Analysis.

PMID 41003599 (2025): aerobic, endurance — VO₂max, Lactate threshold (study note for endurance athletes).

Last updated/Feb 23, 2026, 10:34 PM

Study note • PMID 41003599

Does High-Intensity Interval Training Increase Muscle Strength, Muscle Mass, and Muscle Endurance? A Systematic Review and Meta-Analysis.

Sports (Basel, Switzerland)2025 • DOI 10.3390/sports13090293
Evidence B80/100
Action 1: Default

Low risk + high feasibility for most athletes.

ELI5

In plain language

High-intensity/sprint interval training (HIIT/SIT) improves aerobic and anaerobic performance, but it is unknown if HIIT/SIT increases strength, muscle mass/size, and muscle endurance (ME). (systematic review / meta-analysis; n=1136 participants).

In this systematic review / meta-analysis, the abstract suggests a positive relationship with VO₂max, Lactate threshold. Treat this as a signal, not a guarantee; confirm methods and context in the full paper.

Takeaways

What the abstract suggests

  • Study question: High-intensity/sprint interval training (HIIT/SIT) improves aerobic and anaerobic performance, but it is unknown if HIIT/SIT increases strength, muscle mass/size, and muscle endurance (ME).
  • In this systematic review / meta-analysis, the abstract suggests a positive relationship with VO₂max, Lactate threshold.
  • Population: n=1136 participants.
  • Protocol cues: abstract may omit dose/timing; use the full paper to replicate accurately.

Protocol

Protocol (as reported)

  • Intervention/exposure: aerobic, endurance.
  • Dose/time/duration: abstract doesn’t include enough detail; use the full paper’s methods section.
  • Outcomes: VO₂max, Lactate threshold.
  • Replication note: abstracts often omit adherence and timing; confirm details before changing training or supplementation.

Fit

Who it helps, and who should skip it

Who it helps

  • Athletes similar to the study population (n=1136 participants) working on endurance.
  • Athletes who can measure VO₂max, Lactate threshold with a repeatable workout or time-trial effort.

Who should skip

  • If you have symptoms or conditions that make the intervention risky, get professional guidance.
  • If you’re near race day and can’t safely test, defer the experiment.

Methods

What the study actually did

  • Design: systematic review / meta-analysis.
  • Population: n=1136 participants.
  • Outcomes measured: VO₂max, Lactate threshold.
  • Source: PubMed PMID 41003599 (2025) — Sports (Basel, Switzerland).

Results excerpt

What the abstract reports

Meta-analyses were performed when three or more randomized controlled trials compared HIIT/SIT to a common comparator.

Note: excerpts are short; for full context, read the paper.

Limits

Limitations & bias

  • Abstract-only summaries can miss critical details (population, protocol, adherence, and context).
  • Reviews and consensus statements mix protocols and populations; recommendations may not match your exact constraints.
  • If your context differs (elite vs recreational; cycling vs running), adjust expectations and be conservative.
  • This is performance information, not medical advice.

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Sources