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Study note

The Effect of Pre-Exercise Caffeine and Glucose Ingestion on Endurance Capacity in Hypoxia: A Double-Blind Crossover Trial.

Updated Oct 17, 2026

Human researchNutrients2024Read the source on PubMed

What the study found

Caffeine, glucose and their combination extended the final time-to-exhaustion test compared with placebo in simulated altitude conditions.

Participants and protocol

Eight active young men completed four double-blind crossover cycling trials, including ninety minutes of moderate work followed by a harder exhaustion test in a hypoxic chamber.

What this cannot establish

A percentage gain in time to exhaustion is not the same as that percentage improvement in race time. The small acute study does not establish a personal caffeine dose or a benefit at normal altitude.

Publication details
Record
PubMed 39519456
Publication types
research-article · Randomized Controlled Trial
Indexed subjects
Caffeine · Glucose · Blood Glucose · Exercise · Cross-Over Studies
Source record checked
2026-10-18

Publication type and subject indexing describe the record; they are not a quality grade or proof of a benefit. An abstract does not replace a review of the full methods and results.

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