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Study note

Comparison of the Effect of Endurance, Strength, and Endurance-Strength Training on Inflammatory Markers and Adipokines Levels in Overweight and Obese Adults: Systematic Review and Meta-Analysis of Randomised Trials.

PMID 35742148 (2022): endurance, interval — VO₂max, Lactate threshold (study note for endurance athletes).

Updated Jul 22, 2026

Read the study note

Study note • PMID 35742148

Comparison of the Effect of Endurance, Strength, and Endurance-Strength Training on Inflammatory Markers and Adipokines Levels in Overweight and Obese Adults: Systematic Review and Meta-Analysis of Randomised Trials.

Healthcare (Basel, Switzerland)2022 • DOI 10.3390/healthcare10061098

How to use this page

This note summarizes one study record. Check the participants, methods, results, and limitations before applying it to training.

  • Design signal: systematic review / meta-analysis.
  • Population relevance: mixed/unclear athlete specificity.
  • Consistency: synthesis evidence present.
  • Practical recommendation depends on tolerance, context, and whether it protects training consistency.

ELI5

In plain language

The aim of this meta-analysis was to compare the effects of endurance, strength, and combined training on inflammatory markers and adipokine concentrations in overweight and obese adults. (systematic review / meta-analysis; participants).

In this systematic review / meta-analysis, the abstract doesn’t find a clear benefit for VO₂max, Lactate threshold. Treat this as a signal, not a guarantee; confirm methods and context in the full paper.

Takeaways

What the abstract suggests

  • Study question: The aim of this meta-analysis was to compare the effects of endurance, strength, and combined training on inflammatory markers and adipokine concentrations in overweight and obese adults.
  • In this systematic review / meta-analysis, the abstract doesn’t find a clear benefit for VO₂max, Lactate threshold.
  • Population: participants.
  • Protocol cues: abstract may omit dose/timing; use the full paper to replicate accurately.

Protocol

Protocol (as reported)

  • Intervention/exposure: endurance, interval.
  • Dose/time/duration: abstract doesn’t include enough detail; use the full paper’s methods section.
  • Outcomes: VO₂max, Lactate threshold.
  • Replication note: abstracts often omit adherence and timing; confirm details before changing training or supplementation.

Fit

Who it may help, and who should be cautious

Who it helps

  • Athletes similar to the study population (participants) working on endurance.
  • Athletes who can measure VO₂max, Lactate threshold with a repeatable workout or time-trial effort.

Who should be cautious

  • If you have symptoms or conditions that make the intervention risky, get professional guidance.
  • If you’re near race day and can’t safely test, defer the experiment.

Methods

What the study actually did

  • Design: systematic review / meta-analysis.
  • Population: participants.
  • Outcomes measured: VO₂max, Lactate threshold.
  • Source: PubMed PMID 35742148 (2022) — Healthcare (Basel, Switzerland).

Results excerpt

What the abstract reports

In conclusion, compared with strength training, endurance training is more effective in lowering CRP, IL-6, and visfatin concentrations, while combined training is more beneficial in reducing TNF-alpha levels in overweight and obese adults.

Note: excerpts are short; for full context, read the paper.

Limits

Limitations and bias

  • Abstract-only summaries can miss critical details (population, protocol, adherence, and context).
  • Reviews and consensus statements mix protocols and populations; recommendations may not match your exact constraints.
  • If your context differs (elite vs recreational; cycling vs running), adjust expectations and be conservative.
  • This is performance information, not medical advice.

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Sources