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Study note

Association of skeletal muscle and serum metabolites with maximum power output gains in response to continuous endurance or high-intensity interval training programs: The TIMES study - A randomized controlled trial.

Updated Oct 17, 2026

Human researchPloS one2019Read the source on PubMed

What the study found

Continuous and interval training produced similar average gains in maximal power output. Baseline metabolite patterns were associated with differences in individual gains.

Participants and protocol

Eighty sedentary young men were randomized; seventy completed an eight-week training or control programme. Researchers analysed serum and muscle metabolites using several exploratory approaches.

What this cannot establish

Associations with baseline metabolites do not validate a consumer test for choosing training. Sedentary men and short-term power gains are not equivalent to trained athletes or race outcomes.

Publication details
Record
PubMed 30742692
Publication types
Research Support, Non-U.S. Gov't · research-article · Randomized Controlled Trial · Research Support, N.I.H., Extramural
Indexed subjects
Muscle, Skeletal · Longitudinal Studies · Adolescent · Muscle Strength · Metabolomics
Source record checked
2026-10-18

Publication type and subject indexing describe the record; they are not a quality grade or proof of a benefit. An abstract does not replace a review of the full methods and results.

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