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Women Experience the Same Ergogenic Response to Caffeine as Men.

PMID 30629046 (2019): caffeine — Time-trial performance, Time to exhaustion (study note for endurance athletes).

Last updated/Feb 23, 2026, 10:34 PM

Study note • PMID 30629046

Women Experience the Same Ergogenic Response to Caffeine as Men.

Medicine and science in sports and exercise2019 • DOI 10.1249/MSS.0000000000001885
Evidence B73/100
Action 2: Consider

Worth trying if it fits your goal and context.

ELI5

In plain language

This study aimed to determine whether 1) consumption of caffeine improves endurance cycling performance in women and 2) sex differences exist in the magnitude of the ergogenic and plasma… (randomized trial; trained triathletes).

The abstract doesn’t indicate a clear change in Time-trial performance, Time to exhaustion under the tested conditions. Treat this as a signal, not a guarantee; confirm methods and context in the full paper.

Takeaways

What the abstract suggests

  • Study question: This study aimed to determine whether 1) consumption of caffeine improves endurance cycling performance in women and 2) sex differences exist in the magnitude of the ergogenic and plasma…
  • The abstract doesn’t indicate a clear change in Time-trial performance, Time to exhaustion under the tested conditions.
  • Population: trained triathletes.
  • Protocol cues (title/abstract): 3 mg • 6 mg.

Protocol

Protocol (as reported)

  • Intervention/exposure: caffeine (vs placebo).
  • Dose/time/duration cues in abstract/title: 3 mg • 6 mg.
  • Outcomes: Time-trial performance, Time to exhaustion.
  • Replication note: abstracts often omit adherence and timing; confirm details before changing training or supplementation.

Fit

Who it helps, and who should skip it

Who it helps

  • Athletes similar to the study population (trained triathletes) working on supplements.
  • Athletes who can measure Time-trial performance, Time to exhaustion with a repeatable workout or time-trial effort.

Who should skip

  • If you have symptoms or conditions that make the intervention risky, get professional guidance.
  • If you’re near race day and can’t safely test, defer the experiment.

Methods

What the study actually did

  • Design: randomized trial (double-blind, placebo-controlled).
  • Population: trained triathletes.
  • Comparator: placebo.
  • Outcomes measured: Time-trial performance, Time to exhaustion.
  • Protocol cues mentioned: 3 mg • 6 mg.
  • Source: PubMed PMID 30629046 (2019) — Medicine and science in sports and exercise.

Results excerpt

What the abstract reports

The magnitude of performance improvement was similar for women (mean = 4.3%, 95% CI = 0.4%-8.2%) and men (4.6%, 2.3%-6.8%).

Note: excerpts are short; for full context, read the paper.

Limits

Limitations & bias

  • Abstract-only summaries can miss critical details (population, protocol, adherence, and context).
  • Single studies often don’t generalize to your event, history, and training load; treat results as a starting point.
  • If your context differs (elite vs recreational; cycling vs running), adjust expectations and be conservative.
  • This is performance information, not medical advice.

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Sources