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International society of sports nutrition position stand: nutrient timing.

PMID 28919842 (2017): carbohydrate, carb — Time to exhaustion, Time-trial performance, Fat oxidation (study note for endurance athletes).

Last updated/Feb 23, 2026, 10:34 PM

Study note • PMID 28919842

International society of sports nutrition position stand: nutrient timing.

Journal of the International Society of Sports Nutrition2017 • DOI 10.1186/s12970-017-0189-4
Evidence C60/100
Action 2: Consider

Worth trying if it fits your goal and context.

ELI5

In plain language

The International Society of Sports Nutrition (ISSN) provides an objective and critical review regarding the timing of macronutrients in reference to healthy, exercising adults and in particular highly trained… (review; n=32 well-trained cyclists).

In this review, the abstract suggests a positive relationship with Time-trial performance. Treat this as a signal, not a guarantee; confirm methods and context in the full paper.

Takeaways

What the abstract suggests

  • Study question: The International Society of Sports Nutrition (ISSN) provides an objective and critical review regarding the timing of macronutrients in reference to healthy, exercising adults and in particular highly trained…
  • In this review, the abstract suggests a positive relationship with Time-trial performance.
  • Population: n=32 well-trained cyclists.
  • Protocol cues (full paper): 12 g/kg • 10 g/kg • 4 g/kg • 1.5 g/kg • 2 g/kg • 1.0 g/kg.

Protocol

Protocol (as reported)

  • Intervention/exposure: carbohydrate, carb.
  • Dose/time/duration cues found in the full paper: 12 g/kg • 10 g/kg • 4 g/kg • 1.5 g/kg • 2 g/kg • 1.0 g/kg • 1.2 g/kg • 8 g/kg.
  • Outcomes: Time to exhaustion, Time-trial performance, Fat oxidation.
  • Replication note: abstracts often omit adherence and timing; confirm details before changing training or supplementation.

Fit

Who it helps, and who should skip it

Who it helps

  • Athletes similar to the study population (n=32 well-trained cyclists) working on fueling.
  • Athletes who can measure Time to exhaustion, Time-trial performance, Fat oxidation with a repeatable workout or time-trial effort.

Who should skip

  • If you have symptoms or conditions that make the intervention risky, get professional guidance.
  • If you’re near race day and can’t safely test, defer the experiment.

Methods

What the study actually did

  • Design: review (randomized, double-blind, placebo-controlled, crossover).
  • Population: n=32 well-trained cyclists.
  • Outcomes measured: Time to exhaustion, Time-trial performance, Fat oxidation.
  • Protocol cues mentioned: 1.2 g/kg • 8 mg/kg • 0.8 g/kg • 0.4 g/kg • 0.40 g/kg • 3-8 mg/kg • 4 h • 60 min.
  • Source: PubMed PMID 28919842 (2017) — Journal of the International Society of Sports Nutrition.

Full paper

What the full paper adds

  • Design features (paper): randomized, double-blind, placebo-controlled, crossover.
  • Participants (paper): n=32 well-trained cyclists.
  • More protocol detail (paper): 12 g/kg • 10 g/kg • 4 g/kg • 1.5 g/kg • 2 g/kg • 1.0 g/kg • 1.2 g/kg • 8 g/kg.

Results excerpt

What the abstract reports

More research is needed to determine the influence of combining an exercise program with altered meal frequencies on weight loss and body composition with preliminary research indicating a potential benefit.Ingesting a 20-40 g protein dose (0.25-0.40 g/kg body mass/dose) of a high-quality source…

Note: excerpts are short; for full context, read the paper.

Limits

Limitations & bias

  • Abstract-only summaries can miss critical details (population, protocol, adherence, and context).
  • Reviews and consensus statements mix protocols and populations; recommendations may not match your exact constraints.
  • If your context differs (elite vs recreational; cycling vs running), adjust expectations and be conservative.
  • This is performance information, not medical advice.

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