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Effects of acute supplementation of caffeine and Panax ginseng on endurance running performance in a hot and humid environment.

PMID 25665208 (2011): caffeine — Time-trial performance, Time to exhaustion (study note for endurance athletes).

Last updated/Feb 23, 2026, 11:13 PM

Study note • PMID 25665208

Effects of acute supplementation of caffeine and Panax ginseng on endurance running performance in a hot and humid environment.

Journal of human ergology2011
Evidence C69/100
Action 2: Consider

Worth trying if it fits your goal and context.

ELI5

In plain language

Acute supplementation of Panax ginseng (PG) is known not to impose any significant effect on endurance performance of recreational Malaysian runners, while caffeine augments the ergogenic property of some herbs. (randomized trial; recreational runners).

The abstract doesn’t indicate a clear change in Time-trial performance under the tested conditions. Treat this as a signal, not a guarantee; confirm methods and context in the full paper.

Takeaways

What the abstract suggests

  • Study question: Acute supplementation of Panax ginseng (PG) is known not to impose any significant effect on endurance performance of recreational Malaysian runners, while caffeine augments the ergogenic property of some herbs.
  • The abstract doesn’t indicate a clear change in Time-trial performance under the tested conditions.
  • Population: recreational runners.
  • Protocol cues (title/abstract): 5 mg • 200 mg • 20 minutes • 10 minutes.

Protocol

Protocol (as reported)

  • Intervention/exposure: caffeine (vs placebo).
  • Dose/time/duration cues in abstract/title: 5 mg • 200 mg • 20 minutes • 10 minutes.
  • Outcomes: Time-trial performance, Time to exhaustion.
  • Replication note: abstracts often omit adherence and timing; confirm details before changing training or supplementation.

Fit

Who it helps, and who should skip it

Who it helps

  • Athletes similar to the study population (recreational runners) working on supplements.
  • Athletes who can measure Time-trial performance, Time to exhaustion with a repeatable workout or time-trial effort.

Who should skip

  • If you have symptoms or conditions that make the intervention risky, get professional guidance.
  • If you’re near race day and can’t safely test, defer the experiment.

Methods

What the study actually did

  • Design: randomized trial (double-blind, placebo-controlled).
  • Population: recreational runners.
  • Comparator: placebo.
  • Outcomes measured: Time-trial performance, Time to exhaustion.
  • Protocol cues mentioned: 5 mg • 200 mg • 20 minutes • 10 minutes.
  • Source: PubMed PMID 25665208 (2011) — Journal of human ergology.

Results excerpt

What the abstract reports

Endurance time was significantly different (P < 0.05) between experimental and placebo trials.

Note: excerpts are short; for full context, read the paper.

Limits

Limitations & bias

  • Abstract-only summaries can miss critical details (population, protocol, adherence, and context).
  • Single studies often don’t generalize to your event, history, and training load; treat results as a starting point.
  • If your context differs (elite vs recreational; cycling vs running), adjust expectations and be conservative.
  • This is performance information, not medical advice.

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Sources