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The effect of a caffeinated mouth-rinse on endurance cycling time-trial performance.

PMID 23980239 (2014): caffeine — Time-trial performance, Time to exhaustion (study note for endurance athletes).

Last updated/Feb 23, 2026, 10:34 PM

Study note • PMID 23980239

The effect of a caffeinated mouth-rinse on endurance cycling time-trial performance.

International journal of sport nutrition and exercise metabolism2014 • DOI 10.1123/ijsnem.2013-0103
Evidence B73/100
Action 2: Consider

Worth trying if it fits your goal and context.

ELI5

In plain language

The purpose of this study was to investigate if acute caffeine exposure via mouth-rinse improved endurance cycling time-trial performance in well-trained cyclists. (randomized trial; well-trained cyclists).

The abstract doesn’t indicate a clear change in Time-trial performance under the tested conditions. Treat this as a signal, not a guarantee; confirm methods and context in the full paper.

Takeaways

What the abstract suggests

  • Study question: The purpose of this study was to investigate if acute caffeine exposure via mouth-rinse improved endurance cycling time-trial performance in well-trained cyclists.
  • The abstract doesn’t indicate a clear change in Time-trial performance under the tested conditions.
  • Population: well-trained cyclists.
  • Protocol cues (title/abstract): 35 mg • 60 min.

Protocol

Protocol (as reported)

  • Intervention/exposure: caffeine (vs placebo).
  • Dose/time/duration cues in abstract/title: 35 mg • 60 min.
  • Outcomes: Time-trial performance, Time to exhaustion.
  • Replication note: abstracts often omit adherence and timing; confirm details before changing training or supplementation.

Fit

Who it helps, and who should skip it

Who it helps

  • Athletes similar to the study population (well-trained cyclists) working on supplements.
  • Athletes who can measure Time-trial performance, Time to exhaustion with a repeatable workout or time-trial effort.

Who should skip

  • If you have symptoms or conditions that make the intervention risky, get professional guidance.
  • If you’re near race day and can’t safely test, defer the experiment.

Methods

What the study actually did

  • Design: randomized trial (double-blind, placebo-controlled).
  • Population: well-trained cyclists.
  • Comparator: placebo.
  • Outcomes measured: Time-trial performance, Time to exhaustion.
  • Protocol cues mentioned: 35 mg • 60 min.
  • Source: PubMed PMID 23980239 (2014) — International journal of sport nutrition and exercise metabolism.

Results excerpt

What the abstract reports

No significant improvement in time-trial performance was observed with caffeine (3918 +/- 243 s) compared with placebo mouth-rinse (3940 +/- 227 s).

Note: excerpts are short; for full context, read the paper.

Limits

Limitations & bias

  • Abstract-only summaries can miss critical details (population, protocol, adherence, and context).
  • Single studies often don’t generalize to your event, history, and training load; treat results as a starting point.
  • If your context differs (elite vs recreational; cycling vs running), adjust expectations and be conservative.
  • This is performance information, not medical advice.

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Sources