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The effects of different doses of caffeine on endurance cycling time trial performance.

PMID 22142020 (2012): caffeine — Time-trial performance, Time to exhaustion (study note for endurance athletes).

Last updated/Feb 23, 2026, 10:34 PM

Study note • PMID 22142020

The effects of different doses of caffeine on endurance cycling time trial performance.

Journal of sports sciences2012 • DOI 10.1080/02640414.2011.632431
Evidence B73/100
Action 2: Consider

Worth trying if it fits your goal and context.

ELI5

In plain language

This study investigated the effects of two different doses of caffeine on endurance cycle time trial performance in male athletes. (randomized trial; well-trained cyclists).

The abstract suggests a positive effect on Time-trial performance under the tested conditions. Treat this as a signal, not a guarantee; confirm methods and context in the full paper.

Takeaways

What the abstract suggests

  • Study question: This study investigated the effects of two different doses of caffeine on endurance cycle time trial performance in male athletes.
  • The abstract suggests a positive effect on Time-trial performance under the tested conditions.
  • Population: well-trained cyclists.
  • Protocol cues (title/abstract): 6 mg • 3 mg • 90 min • 60 min.

Protocol

Protocol (as reported)

  • Intervention/exposure: caffeine (vs placebo).
  • Dose/time/duration cues in abstract/title: 6 mg • 3 mg • 90 min • 60 min.
  • Outcomes: Time-trial performance, Time to exhaustion.
  • Replication note: abstracts often omit adherence and timing; confirm details before changing training or supplementation.

Fit

Who it helps, and who should skip it

Who it helps

  • Athletes similar to the study population (well-trained cyclists) working on supplements.
  • Athletes who can measure Time-trial performance, Time to exhaustion with a repeatable workout or time-trial effort.

Who should skip

  • If you have symptoms or conditions that make the intervention risky, get professional guidance.
  • If you’re near race day and can’t safely test, defer the experiment.

Methods

What the study actually did

  • Design: randomized trial (double-blind, placebo-controlled).
  • Population: well-trained cyclists.
  • Comparator: placebo.
  • Outcomes measured: Time-trial performance, Time to exhaustion.
  • Protocol cues mentioned: 6 mg • 3 mg • 90 min • 60 min.
  • Source: PubMed PMID 22142020 (2012) — Journal of sports sciences.

Results excerpt

What the abstract reports

Exercise performance was significantly (P < 0.05) improved with both caffeine treatments as compared to placebo (4.2% with 3 mg x kg(-1) body mass and 2.9% with 6 mg x kg(-1) body mass).

Note: excerpts are short; for full context, read the paper.

Limits

Limitations & bias

  • Abstract-only summaries can miss critical details (population, protocol, adherence, and context).
  • Single studies often don’t generalize to your event, history, and training load; treat results as a starting point.
  • If your context differs (elite vs recreational; cycling vs running), adjust expectations and be conservative.
  • This is performance information, not medical advice.

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Sources