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Influence of carbohydrate ingestion on blood glucose and performance in runners.

PMID 1299501 (1992): carbohydrate, carb — Time to exhaustion, Time-trial performance, Fat oxidation (study note for endurance athletes).

Last updated/Feb 23, 2026, 10:34 PM

Study note • PMID 1299501

Influence of carbohydrate ingestion on blood glucose and performance in runners.

International journal of sport nutrition1992 • DOI 10.1123/ijsn.2.4.317
Evidence B74/100
Action 1: Default

Low risk + high feasibility for most athletes.

ELI5

In plain language

Ten trained male runners performed a treadmill exercise test at 80% VO2max under two experimental conditions, carbohydrate (CHO, 7% carbohydrate) and placebo (P), to determine the effect of carbohydrate… (randomized trial; trained runners).

The abstract suggests a positive effect on Time to exhaustion, Time-trial performance under the tested conditions. Treat this as a signal, not a guarantee; confirm methods and context in the full paper.

Takeaways

What the abstract suggests

  • Study question: Ten trained male runners performed a treadmill exercise test at 80% VO2max under two experimental conditions, carbohydrate (CHO, 7% carbohydrate) and placebo (P), to determine the effect of carbohydrate…
  • The abstract suggests a positive effect on Time to exhaustion, Time-trial performance under the tested conditions.
  • Population: trained runners.
  • Protocol cues (title/abstract): 5 min • 25 min • 27 min • 80% VO2max.

Protocol

Protocol (as reported)

  • Intervention/exposure: carbohydrate, carb (vs placebo).
  • Dose/time/duration cues in abstract/title: 5 min • 25 min • 27 min • 80% VO2max.
  • Outcomes: Time to exhaustion, Time-trial performance, Fat oxidation.
  • Replication note: abstracts often omit adherence and timing; confirm details before changing training or supplementation.

Fit

Who it helps, and who should skip it

Who it helps

  • Athletes similar to the study population (trained runners) working on fueling.
  • Athletes who can measure Time to exhaustion, Time-trial performance, Fat oxidation with a repeatable workout or time-trial effort.

Who should skip

  • If you have symptoms or conditions that make the intervention risky, get professional guidance.
  • If you’re near race day and can’t safely test, defer the experiment.

Methods

What the study actually did

  • Design: randomized trial (double-blind, placebo-controlled).
  • Population: trained runners.
  • Comparator: placebo.
  • Outcomes measured: Time to exhaustion, Time-trial performance, Fat oxidation.
  • Protocol cues mentioned: 5 min • 25 min • 27 min • 80% VO2max.
  • Source: PubMed PMID 1299501 (1992) — International journal of sport nutrition.

Results excerpt

What the abstract reports

Performance was enhanced by 29.4% (p < 0.05) during CHO (115 +/- 25 min) compared to P (92 +/- 27 min).

Note: excerpts are short; for full context, read the paper.

Limits

Limitations & bias

  • Abstract-only summaries can miss critical details (population, protocol, adherence, and context).
  • Single studies often don’t generalize to your event, history, and training load; treat results as a starting point.
  • If your context differs (elite vs recreational; cycling vs running), adjust expectations and be conservative.
  • This is performance information, not medical advice.

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Sources