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Physiological determinants of endurance exercise performance.

PMID 10668757 (1999): carbohydrate, carb — Time to exhaustion, Time-trial performance, Fat oxidation (study note for endurance athletes).

Last updated/Feb 23, 2026, 11:13 PM

Study note • PMID 10668757

Physiological determinants of endurance exercise performance.

Journal of science and medicine in sport1999 • DOI 10.1016/s1440-2440(99)80172-8
Evidence C60/100
Action 2: Consider

Worth trying if it fits your goal and context.

ELI5

In plain language

Performance in endurance events is typically evaluated by the power or velocity that can be maintained for durations of 30 min. (review; athletes).

In this review, the abstract reports associations involving Time-trial performance (not necessarily causation). Treat this as a signal, not a guarantee; confirm methods and context in the full paper.

Takeaways

What the abstract suggests

  • Study question: Performance in endurance events is typically evaluated by the power or velocity that can be maintained for durations of 30 min.
  • In this review, the abstract reports associations involving Time-trial performance (not necessarily causation).
  • Population: athletes.
  • Protocol cues (title/abstract): 30 min.

Protocol

Protocol (as reported)

  • Intervention/exposure: carbohydrate, carb.
  • Dose/time/duration cues in abstract/title: 30 min.
  • Outcomes: Time to exhaustion, Time-trial performance, Fat oxidation.
  • Replication note: abstracts often omit adherence and timing; confirm details before changing training or supplementation.

Fit

Who it helps, and who should skip it

Who it helps

  • Athletes similar to the study population (athletes) working on fueling.
  • Athletes who can measure Time to exhaustion, Time-trial performance, Fat oxidation with a repeatable workout or time-trial effort.

Who should skip

  • If you have symptoms or conditions that make the intervention risky, get professional guidance.
  • If you’re near race day and can’t safely test, defer the experiment.

Methods

What the study actually did

  • Design: review.
  • Population: athletes.
  • Outcomes measured: Time to exhaustion, Time-trial performance, Fat oxidation.
  • Protocol cues mentioned: 30 min.
  • Source: PubMed PMID 10668757 (1999) — Journal of science and medicine in sport.

Results excerpt

What the abstract reports

The combination of dehydration and hyperthermia during exercise causes large reductions in cardiac output and blood flow to the exercising musculature, and thus has a large potential to impair endurance performance.

Note: excerpts are short; for full context, read the paper.

Limits

Limitations & bias

  • Abstract-only summaries can miss critical details (population, protocol, adherence, and context).
  • Reviews and consensus statements mix protocols and populations; recommendations may not match your exact constraints.
  • If your context differs (elite vs recreational; cycling vs running), adjust expectations and be conservative.
  • This is performance information, not medical advice.

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Sources