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Strength Training Improves Running Economy Durability and Fatigued High-Intensity Performance in Well-Trained Male Runners: A Randomized Control Trial.

PMID 40016936 (2025): endurance, interval — VO₂max, Lactate threshold (study note for endurance athletes).

Last updated/Feb 23, 2026, 10:34 PM

Study note • PMID 40016936

Strength Training Improves Running Economy Durability and Fatigued High-Intensity Performance in Well-Trained Male Runners: A Randomized Control Trial.

Medicine and science in sports and exercise2025 • DOI 10.1249/MSS.0000000000003685
Evidence B71/100
Action 1: Default

Low risk + high feasibility for most athletes.

ELI5

In plain language

INTRODUCTION: Strength training improves running economy (RE) in a nonfatigued state and performance after prolonged exercise at moderate intensity. (randomized trial; n=14 well-trained runners).

The abstract suggests a positive effect on VO₂max, Lactate threshold under the tested conditions. Treat this as a signal, not a guarantee; confirm methods and context in the full paper.

Takeaways

What the abstract suggests

  • Study question: INTRODUCTION: Strength training improves running economy (RE) in a nonfatigued state and performance after prolonged exercise at moderate intensity.
  • The abstract suggests a positive effect on VO₂max, Lactate threshold under the tested conditions.
  • Population: n=14 well-trained runners.
  • Protocol cues (title/abstract): 90 min • 10 km • 4 km • 6 km.

Protocol

Protocol (as reported)

  • Intervention/exposure: endurance, interval (vs comparison group).
  • Dose/time/duration cues in abstract/title: 90 min • 10 km • 4 km • 6 km.
  • Outcomes: VO₂max, Lactate threshold.
  • Replication note: abstracts often omit adherence and timing; confirm details before changing training or supplementation.

Fit

Who it helps, and who should skip it

Who it helps

  • Athletes similar to the study population (n=14 well-trained runners) working on endurance.
  • Athletes who can measure VO₂max, Lactate threshold with a repeatable workout or time-trial effort.

Who should skip

  • If you have symptoms or conditions that make the intervention risky, get professional guidance.
  • If you’re near race day and can’t safely test, defer the experiment.

Methods

What the study actually did

  • Design: randomized trial.
  • Population: n=14 well-trained runners.
  • Comparator: comparison group.
  • Outcomes measured: VO₂max, Lactate threshold.
  • Protocol cues mentioned: 90 min • 10 km • 4 km • 6 km.
  • Source: PubMed PMID 40016936 (2025) — Medicine and science in sports and exercise.

Results excerpt

What the abstract reports

A large interaction effect of training-group-run time was found for RE ( P = 0.003, etap2 = 0.13), with E + S improving versus E at 90 min (-2.1% vs +0.6%; P = 0.04).

Note: excerpts are short; for full context, read the paper.

Limits

Limitations & bias

  • Abstract-only summaries can miss critical details (population, protocol, adherence, and context).
  • Single studies often don’t generalize to your event, history, and training load; treat results as a starting point.
  • If your context differs (elite vs recreational; cycling vs running), adjust expectations and be conservative.
  • This is performance information, not medical advice.

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